Sex education has the potential to be a powerful way to educate children and adolescents about the risks and implications of sex. There currently is a debate about what type of information should be appropriately delivered to students in school; supporters of Comprehensive-Based sex education argue that information regarding Sexually Transmitted Diseases and contraceptives should be delivered to students, while supporters of Abstinence-Only sex education hold that the only method of safe sex that should be taught to students is abstinence. There are an alarming number of children and adolescents dealing with the consequences of unprotected sex, so sex education programs that reduce this number most effectively should be delivered to students in schools. It was hypothesized that children and adolescents who received Comprehensive-Based sex education would be more knowledgeable about safe sex, and practice safe sex more often in their lives. A quantitative study was distributed to 45 college-aged students to learn what type of sex education they received in school, and assess their safe sex knowledge and practices. The results supported the hypothesis that students who received Comprehensive-Based sex education knew more about safe sex practices and were able to put them into practice more often, but the results were not statistically significant. More extensive research should be conducted to a larger group of students who had just received their sex education in school in order to assess what type of sex education should be administered in schools.