Subject Area

Biology

Description

Major: Biology and Mathematics
Faculty Mentor: Fr. Nicanor Austriaco O.P., Biology

Parkinson’s Disease (PD) is the second most common, incurable neurodegenerative disorder worldwide. PD patients have accumulations of abnormal proteins called Lewy Bodies (LBs) within their neurons that trigger cell death. Damaged and dead neurons lead to decline in dopamine levels, triggering the symptoms of Parkinson’s such as muscle stiffness, tremors, and slowed movement. Numerous studies have shown that the human protein, alpha-synuclein and Tau, are two major components of Lewy Bodies. To study the relationship between protein aggregation and cell death, I have created a system to co-overexpress human alpha-synuclein fused to GFP and human Tau fused to mCherry in the budding yeast, Saccharomyces.

Publisher

Providence College

Date

4-22-2020

Start Date

4-22-2020 12:00 AM

Type

Poster

.pdf

Language

English

Included in

Biology Commons

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.