Differentiation and Maturation of Cerebral Organoids from APOE3/APOE4 Stem Cell Lines
Subject Area
Biology
Description
Christopher Walsh ’23, Majors: Biology and Psychology
Hayden Lens ’23, Major: Biology
Colin Luca ’23, Major: Biology
Isabella Glennon ’25, Majors: Biology and Psychology
Ryan Fodero ’23, Economics
Faculty Mentor: Dr. Chuck Toth, Biology
The APOE4 gene is a high-risk factor for the development of Alzheimer’s Disease in humans. In our project, we have grown cerebral organoids (mini-brains) using induced pluripotent stem cells containing the APOE4/APOE3 mutation. After the organoids were fully grown, they were tested from biomarkers commonly found in Alzheimer’s Disease.
Publisher
Providence College
Date
4-26-2022
Type
Poster
Language
English
COinS
